Note: “Hamilton Morris” in this piece is a fictional alias. It is not the real journalist and chemist of that name. It’s a playful stand-in for an anonymous psychonaut who did the work described below. Everything attributed to him here is invented dialogue built around real experimental details shared with me anonymously. Matthew Stahl is a real person, and the recipe discussed is his, adapted from his book LSI.
For roughly two millennia, once a year, thousands of initiates walked from Athens to the sanctuary at Eleusis to drink a beverage called kykeon. Plato likely went. Cicero later wrote that Eleusis gave people “a reason not merely to live in joy, but to die with a better hope.” The Homeric Hymn to Demeter describes the rite in reverent language, but also evasively because the rites were considered sacred and initiates were sworn to secrecy. For nearly two thousand years, the secret remained remarkably well guarded. Finally, outside pressure shut the practice down. Roman Emperor Theodosius I effectively banned pagan worship in 392 CE. A few years later the sanctuary at Eleusis was looted and devastated by invading Goths led by Alaric. The last initiates who knew it firsthand eventually died, and the secret was lost.
“Psychedelic Medicine and Internal Family Systems (IFS) Therapy: A Clinical Skills Manual” (2026) lays out a clinical protocol (IFS-PAT) for integrating Internal Family Systems therapy with psychedelics. The authors walk through the full arc of a course of treatment. The manual is aimed at practicing clinicians rather than a general audience. I’d been eagerly waiting for these authors to put their cards on the table. Now that they have, three things stand out: two sloppy sections, one recurring confusion that runs deeper than either, and a guess about why.
Noonautics and the Trace Institute announced a research collaboration to build a mathematical framework for the human DMT experience. Noonautics, led by neurobiologist Dr. Andrew Gallimore, will use the extended state DMTx protocol, developed with Dr. Rick Strassman, to extend DMT experiences from minutes to hours so trained observers can make sustained observations from inside the state. The Trace Institute, led by Professor Emeritus Donald Hoffman, will apply trace logic and conscious realism, an observer-centered model of reality, to give the resulting phenomenology a quantitative structure.
I commented on HHS-OASH-2026-0232-0001, the Request for Information regarding the proposed 7-hydroxymitragynine (7-OH) scheduling threshold.
Comment Tracking Number: mry-8nrd-tg5g
I am submitting this comment in response to the Request for Information regarding the proposed 7-hydroxymitragynine (7-OH) scheduling threshold (Docket HHS-OASH-2026-0232).
First, on the imminent-hazard finding itself: temporary scheduling under 21 U.S.C. 811(h)(1) is meant to address genuinely urgent threats that cannot wait for ordinary scheduling procedure. I would ask OASH to specify the comparative risk data—overdose rate, dependence liability, and ER visits per capita of users—that establishes 7-OH at the proposed threshold as more hazardous than legal, widely available substances such as alcohol, which carries well-documented acute toxicity and tens of thousands of attributable deaths annually without triggering emergency scheduling. Absent that comparative showing, it is difficult to evaluate whether the proposed threshold reflects an evidentiary emergency finding or a policy preference.
Here, the blend and justification reflect male sexual response. That’s the experience I can speak to directly. Women may find a different recipe works better. One worth trying: Δ8-THC:CBN:CBC in a 6:2:1 ratio.
Most cannabis formulations, built around just THC and CBD, can work for intimacy—but they require a certain amount of mental effort to stay in a good headspace. That’s the kind of effort you don’t need to be making.
I recently tried 5-MAPB (5-(2-methylaminopropyl)benzofuran) at 80mg on a single occasion—my first experience with an MDMA-like compound. This gave me a useful point of comparison with psilomethoxin (Pm).
In my judgment, Pm at 0.5–1g most closely resembles 5-MAPB. Below that range, Pm is too subtle; above it, the experience pulls inward too firmly in a way that diverges from the 5-MAPB character.
The comparison confirmed differences I had suspected. 5-MAPB is a stimulant—sleep on the day of administration was a challenge. Pm is not a stimulant; as noted in the original case report, falling asleep at the peak is possible.
September 25, 2026
